Here we list the projects available right now. Come and talk to us if you are interested in doing your Master's thesis! We will do our best to figure out a good project for you!
Available Master Thesis project
Applied Raman Spectroscopy: Fluorescence background suppression by shifted excitation Raman difference techniques
Raman spectroscopy is a versatile and robust optical technique used in several applications for analysis with identification and quantification of chemical species. Research concerning Raman spectroscopy has a long tradition at Lund University where it has been developed and applied in for example medicine and combustion research.
There are a number of advantages that makes Raman spectroscopy an ideal candidate for applied spectroscopy since the experimental configuration, basically consisting of a laser and a spectrometer, is rather straight forward. Moreover, the molecular fingerprint is accessible in the spectral domain which is an advantage from an analysis standpoint since you do not rely on absolute signal values. There are, however, a number of challenges in Raman spectroscopy where interfering fluorescence signals is a major hurdle that has to be reduced to provide Raman spectra of sufficient quality for systematic analysis.
This project is initiated by Lund University and Serstech, a Lund-based company that develops hand-held Raman spectrometers for on-the-fly chemical analysis. Serstech started in 2006 and has since been working with a vision of making spectrometers small, accurate and cost-efficient.
The goal of the proposed masters project is to investigate the possibility of applying a spectroscopic method to reject fluorescence background by shifting the laser pump wavelength and study the spectral response of the signal. The spectral content of the Raman signal will shift with the laser pump frequency whereas the interfering fluorescence background will (in principle) be unaffected. The project plan concern setting up an experimental work station, carry out experiments and analyze the data, all with the aim of working with optical components used in Serstec Raman instruments.
Contact persons at the Division of Combustion Physics:
For Master's projects with the Applied Molecular Spectroscopy and Remote Sensing group
For Master's projects with the Chemical kinetics group
Master thesis in Monitoring oxygen in lungs using GAs in Scattering Media Absorption Spectroscopy
Our group works with medical laser diagnostics, specifically aimed at monitoring of oxygen in lungs using the GAs in Scattering Media Absorption Spectroscopy (GASMAS) technique. This has found successful application in the monitoring of the lung function for preterm infants, where careful monitoring of spatially distributed oxygen content can lead to optimal respiratory support and prompt detection and treatment of complications. Applications in larger children and adults have not been possible so far, due to the longer light paths involved leading to extremely low light intensities reaching the detector.
In this thesis work, you will design and build a tapered amplifier system to increase the laser power available in the current GASMAS laser system from powers of 10 mW to well over 1 W. Once the system is built, you will investigate the detection ability in phantoms of increasing similarity to the adult lung case, starting with simpler scattering models in the lab, such as a large broiler filled with scattering material (e.g., sponge), passing via a realistic phantom lung, and (if time allows) finally to do monitoring on an excised wild boar lung. The project will be partly done in collaboration with the GPX Medical company.
Supervisor: Associate Lecturer Anna-Lena Sahlberg (Dept. Physics, Lund University)